I had to do a few additional tasks to get this to work:
1. Be very careful to only include references to Enterprise Library that are really needed
2. Merge Enterprise Library assemblies using ilmerge (see Reply 21 here http://forums.crystaltech.com/index.php/topic,29566.msg175721.html#msg175721, referring to http://research.microsoft.com/~mbarnett/ILMerge.aspx )
3. Update References for all generated nettiers projects to use the merged single assembly