How do you mean? I believe nettiers objects support loading data for many to many relationships via Entity.[ChildType]Collection and Entity.[Type]_Collection_From_[ChildType]. If you deep load all these (ChildType and Type) and use a binding source (or anything that has a currency manager) then you should be able to bind without any hustles. e.g if you have the types User, UserRole and Role in a many to many relationship you can deep load using:
UserService userService = new UserService();
User user = userService.GetByUserID(1);
userService.DeepLoad(user, true, Data.DeepLoadType.IncludeChildren, new Type[] {typeof(TList<UserRole>), typeof(TList<Role>) });
Use two binding sources UsersBS and RolesBS. Set UserBS.DataSource = user and RoleBS.DataSource = user.RoleCollection_From_UserRole.
This should work.